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Quality products?make an important contribution to long-term revenue and profitability. 99% Purity Commercial production XANTHOTOXOL 2009-24-7 with Cheapest Price
1.What is the XANTHOTOXOL ?
A hydroxylated psoralen that inhibits neutrophil infiltration and brain edema induced by focal cerebral ischemia-reperfusion injury in rats. A potentially useful antiarrhythmic agent. It has been shown to be effective in the prevention of ventricular fibrillation of mice induced by chloroform, of rats induced by calcium chloride, and in treatment of rat arrhythmia induced by aconitine. Recent studies show that it may also have antioxidant and anticancer activities.
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![9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one](/upload/2026/4/6df002d42bfd49fa9d097800e92141c8_638fa68d-a35c-49fb-865a-2759f6edff38.png)
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298-81-7
9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one
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2009-24-7
8-hydroxypsoralen
| Conditions | Yield |
|---|---|
|
With
boron tribromide;
In
dichloromethane;
|
98%
|
|
With
boron tribromide;
In
dichloromethane;
at 0 - 20 ℃;
for 10h;
Inert atmosphere;
|
97%
|
|
With
boron tribromide;
In
dichloromethane;
at 0 ℃;
for 4h;
|
96%
|
|
With
boron tribromide;
In
dichloromethane;
at 20 ℃;
for 4h;
|
94.5%
|
|
With
aluminium trichloride;
In
dichloromethane;
at 20 ℃;
for 20h;
|
93%
|
|
With
boron tribromide;
In
dichloromethane;
at 0 ℃;
for 3h;
Inert atmosphere;
|
93%
|
|
With
boron tribromide;
In
dichloromethane;
at 20 ℃;
for 4h;
|
92%
|
|
With
boron tribromide;
In
dichloromethane;
at 0 ℃;
for 1h;
|
92%
|
|
9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one;
In
dichloromethane;
for 0.25h;
Cooling with ice;
With
boron tribromide;
In
dichloromethane;
at -5 - 0 ℃;
for 4h;
Inert atmosphere;
|
91%
|
|
9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one;
With
boron tribromide;
In
dichloromethane;
Cooling with ice;
Reflux;
With
water;
|
90%
|
|
With
boron tribromide;
In
dichloromethane;
at 0 - 20 ℃;
Inert atmosphere;
|
90%
|
|
With
boron tribromide;
In
dichloromethane; water;
at 20 ℃;
for 4.5h;
Inert atmosphere;
Cooling with ice;
|
90%
|
|
With
dichloromethane; boron tribromide;
at 0 ℃;
for 12h;
|
90%
|
|
9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one;
With
boron tribromide;
In
dichloromethane;
at 20 ℃;
for 4h;
Inert atmosphere;
With
sodium hydrogencarbonate;
In
dichloromethane; water;
for 1h;
|
89%
|
|
With
aluminum (III) chloride;
In
dichloromethane;
at 0 - 27 ℃;
for 5h;
|
85%
|
|
With
boron tribromide;
In
dichloromethane;
at 10 ℃;
for 4h;
|
82.1%
|
|
With
boron tribromide;
In
dichloromethane;
at 0 ℃;
for 4h;
Inert atmosphere;
|
81%
|
|
With
pyridine hydrochloride;
at 220 - 230 ℃;
for 0.416667h;
|
77%
|
|
With
boron tribromide;
In
dichloromethane;
at 0 ℃;
for 2h;
|
71%
|
|
With
aluminum (III) chloride;
In
dichloromethane;
at 20 ℃;
for 24h;
|
67%
|
|
With
pyridine hydrochloride;
at 180 - 200 ℃;
for 3h;
|
50%
|
|
With
aniline hydrochloride;
at 200 ℃;
|
|
|
With
aluminium trichloride;
at 140 ℃;
|
|
|
With
magnesium iodide;
at 170 ℃;
|
|
|
With
trimethylsilyl iodide;
Yield given;
|
|
|
With
iodine; magnesium;
|
|
|
With
aluminium trichloride;
In
dichloromethane;
at 20 ℃;
|
|
|
With
pyridine hydrochloride;
for 0.116667h;
Microwave irradiation;
Heating;
|
|
|
With
boron trifluoride;
In
dichloromethane;
at -5 - 0 ℃;
for 4h;
|
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-
482-44-0
imperatorin
-
-
2009-24-7
8-hydroxypsoralen
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
methanol; water;
|
100%
|
|
With
ferrous(II) sulfate heptahydrate; dipotassium hydrogenphosphate; magnesium sulfate heptahydrate; D-glucose; potassium chloride; water; Sucrose;
In
dimethyl sulfoxide;
at 27 ℃;
for 288h;
|
64%
|
|
With
hydrogenchloride;
In
ethanol;
for 2h;
Heating;
|
7.0 g
|
|
With
hydrogenchloride;
In
ethanol;
for 2h;
Heating;
|
14.5 g
|
|
In
methanol; water;
Irradiation;
|
|
|
In
methanol; water;
Product distribution;
Irradiation;
UV light (λ = 350 nm);
|
|
|
With
sulfuric acid;
In
tetrahydrofuran; water;
at 20 ℃;
for 6h;
|
|
|
With
sulfuric acid; water;
In
tetrahydrofuran;
at 20 ℃;
for 6h;
|
2.What is the CAS number for XANTHOTOXOL ?
The CAS number of XANTHOTOXOL is 2009-24-7.
More information of XANTHOTOXOL 2009-24-7 are:
|
CAS?Number |
2009-24-7 |
|
Density |
1.526 g/cm3 |
|
Melting Point |
250 °C |
|
Boiling Point |
428.1 °C at 760 mmHg |
|
Flash Point |
212.7 °C |
|
Vapor Pressure |
6.22E-08mmHg at 25°C |
|
Refractive Index |
1.71 |
|
HS CODE |
29329990 |
|
PSA |
63.58000 |
|
LogP |
2.24480 |
|
Pka |
5.74±0.20(Predicted) |
3.What are another words for XANTHOTOXOL ?
Synonyms?for?XANTHOTOXOL 2009-24-7:5-Benzofuranacrylicacid, 6,7-dihydroxy-, d-lactone (7CI);Xanthotoxol (6CI);2-Propenoic acid, 3-(6,7-dihydroxy-5-benzofuranyl)-,d-lactone;8-Hydroxypsoralen;NSC401269;Psoralen, 8-hydroxy-;9-Hydroxy-7H-furo[3,2-g]chromen-7-one;
4.What is the molecular formula of XANTHOTOXOL?
The chemical formula of ?XANTHOTOXOL is?C11H6O4 which containing 11 Carbon atoms,6 Hydrogen atoms and 4 Oxygen atoms,and the molecular weight of??XANTHOTOXOL?is 202.166.
5.What is XANTHOTOXOL (2009-24-7) used for?
Xanthotoxol is a coumarin and a major component in C. monnieri that has diverse biological activities. It inhibits proliferation of HeLa and HepG2 cells in vitro (IC50s = 23.59 and 15.57 μM, respectively). Xanthotoxol increases histamine release from mast cells and decreases secretion of TNF-α, IL-4, and IL-1β from RBL-2H3 cells induced by DNP-human serum albumin (DNP-HSA). It is nematocidal against M. incognita (IC50 = 68 mg/L). In vivo, xanthotoxol inhibits predatory mouse and rat killing behavior in dogs and cats when administered at doses ranging from 3 to 100 mg/kg and 5 to 20 mg/kg, respectively. It reduces amphetamine-induced hypermobility in mice and hamsters. Xanthotoxol (5 and 10 mg/kg) reduces brain edema, neutrophil infiltration, blood-brain barrier disruption, production of IL-1β, TNF-α, IL-8, and nitric oxide (NO), and levels of intercellular adhesion molecule-1 (ICAM-1) and E-selectin in a rat model of focal cerebral ischemia.
InChI:InChI=1/C11H6O4/c12-8-2-1-6-5-7-3-4-14-10(7)9(13)11(6)15-8/h1-5,13H
Relevant articles related to XANTHOTOXOL:
|
Article |
Source |
|
Synthesis of 8-geranyloxypsoralen analogues and their evaluation as inhibitors of CYP3A4 |
Row,Brown,Stachulski,Lennard , p. 3865 - 3871 (2006) |
|
Noncovalent attachment of psoralen derivatives with DNA: Hartree-Fock and density functional studies on the probes. |
El-Gogary, Tarek M,El-Gendy, Eman M , p. 2635 - 2644 (2003) |
6.Buy XANTHOTOXOL with the best price .
Henan Fine Chemicals Co., Ltd is a quality supplier of XANTHOTOXOL. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on XANTHOTOXOL 2009-24-7.
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