2-Acetylphenothiazine

Buy Good Quality 2-Acetylphenothiazine 6631-94-3 with a minimum purity of 99% We supply high quality 2-Acetylphenothiazine (CAS 6631-94-3), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the 2-Acetylphenothiazine ?

2-Acetylphenothiazine is mustard-colored powder, while it's Molecular Formula is C14H11 N O S. 2-Acetylphenothiazine was used as a NADPH oxidase (NOX) inhibitor in human platelet functional responses and intracellular signaling pathways. It was also used in the synthesis of 2-phenothiazin-2′-yl-cinchoninic acid derivatives.

What is the CAS number for 2-Acetylphenothiazine ?

The CAS number of 2-Acetylphenothiazine is 6631-94-3.

More information of 2-Acetylphenothiazine 6631-94-3 are:

What is 2-Acetylphenothiazine (6631-94-3) used for?

2-Acetylphenothiazine (2-APT) is a selective, cell-active inhibitor of NADPH oxidase 1 (NOX1) that blocks the generation of reactive oxygen species (ROS) in HT-29 cells with an IC50 value of 0.129 μM. It does not affect xanthine oxidase-dependent or mitochondrial ROS generation. 2-APT prevents ROS-dependent formation of ECM-degrading invadopodia in colon cancer cells. It also abolishes collagen-induced superoxide production by platelets (IC50 = 306 nM), preventing platelet aggregation and thrombus formation. 2-APT protects beta cells from cytokine-induced apoptosis by inhibiting NOX1. 2-APT can also activate the human transient receptor potential ankyrin 1 (TRPA1) nociceptor at 1-30 μM.

InChI:InChI=1/C14H11NOS/c1-9(16)10-6-7-14-12(8-10)15-11-4-2-3-5-13(11)17-14/h2-8,15H,1H3

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How to get the best price on 2-Acetylphenothiazine?

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